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At-Home Female Saliva Hormone Panel
Evaluates DHEA & Cortisol Balance
Tests Estradiol, Progesterone & Testosterone

You have been told your labs are “normal,” but you do not feel normal. Your energy is not what it used to be. Your sleep has changed. Your mood feels unpredictable. Your libido has faded. And you are left wondering whether it is stress, aging, or something else entirely.
If that sounds familiar, looking at your hormones together rather than one at a time may give you and your healthcare provider useful information to work with. This at-home saliva panel, processed by ZRT Laboratory, measures the bioavailable forms of five key hormones in one kit: estradiol, progesterone, testosterone, DHEA-S, and cortisol.
Instead of testing one hormone and hoping you picked the right one, this panel measures five together, which helps reveal patterns that are hard to see when each hormone is viewed in isolation.
Your symptoms are often shaped by how estrogen, progesterone, testosterone, DHEA-S and cortisol interact, not simply by whether one is high or low. That is exactly why this panel measures them together.
Hormones rarely work alone. This panel looks at how they work together.
This panel may be worth considering if you are experiencing:
This is a wellness and monitoring tool, not an emergency or stand-alone diagnostic test, and it does not replace evaluation by your physician.
Saliva testing is also not appropriate if you use sublingual or troche (lozenge or drop) hormones, because the hormone can contaminate the sample directly and produce falsely high saliva levels. ZRT states that blood spot testing is the preferred option for these patients. Flourish compounds sublingual hormones, so if that is you, call 405-751-3333 before ordering and we will route you to the right method.
If you produce very little saliva, collection may be difficult. And this saliva panel does not include thyroid markers. If thyroid is part of your question, a combined saliva and blood spot profile fits better, and the Flourish team can point you to it.
Most of the sex and adrenal hormones in your bloodstream are bound to carrier proteins and are not available to your tissues. Saliva measures the free, bioavailable fraction, the portion that actually reaches and acts on cells, which is why ZRT describes saliva as relating more closely to symptoms of excess or deficiency. It is also non-invasive and collected at home. For women using topical creams or gels, saliva reflects hormone delivery to tissue better than standard venous blood does.
Each hormone tells part of the story. The value is in seeing them side by side.
Your ZRT report shows each hormone against its expected range, so you and your provider can spot patterns, and what people with those patterns commonly describe:
These are common experiences, not diagnoses. Seeing the pattern gives you and your provider an objective starting point, and because the panel can be repeated, an objective way to track change over time or fine-tune a hormone plan.
Every ZRT hormone test is processed by the same laboratory. What makes ordering through Flourish different is what happens after your results arrive.
Instead of simply receiving a lab report, you have access to pharmacists, nutrition professionals, telehealth services and a compounding pharmacy that can help you understand your results and discuss appropriate next steps with your healthcare provider.
Our goal isn't just to sell a test. It's to help you understand what your results mean.
At-home saliva collection materials with full instructions, and prepaid shipping to ZRT Laboratory. Results are typically ready in about two weeks.
Your results are delivered to you and to the Flourish pharmacy team. If you would like help interpreting them, an optional review with a Flourish pharmacist or nutritionist is available. No appointment is required to receive your results, and there is no obligation.
What hormones does this test measure?
Five, in saliva: estradiol, progesterone, testosterone, DHEA-S and cortisol, in their bioavailable (free) forms. It is processed by ZRT Laboratory.
Why measure five hormones instead of one?
Hormones work together, so symptoms usually reflect more than one of them. Testing a single hormone risks missing the pattern. Measuring five at once helps you and your provider see how they relate, instead of guessing which one to check.
Why do I suddenly feel different in my 40s?
Many women notice shifting energy, sleep, mood and cycles in their 40s as estrogen and progesterone begin to fluctuate during the years before menopause. A hormone panel will not by itself diagnose that transition, but it can show where your levels sit so you and your provider can interpret your symptoms with real data.
How do I know if I am in perimenopause?
Perimenopause is usually recognized by a cluster of changes, including irregular cycles, hot flashes, and sleep and mood shifts, often starting in the 40s, and it is a clinical assessment your provider makes. Hormone levels fluctuate during this time, so this panel is most useful as one input to that conversation rather than a stand-alone answer.
Can a hormone imbalance affect my sleep?
Sleep is influenced by several of the hormones in this panel, estradiol, progesterone and cortisol among them, so changes in any of them are commonly associated with disrupted sleep. Seeing them together can help identify what is worth discussing with your provider.
Can a hormone imbalance cause anxiety or mood changes?
Estrogen, progesterone and cortisol all interact with mood, and shifts in them are commonly associated with irritability, low mood and anxiety-like symptoms. This panel gives an objective look at those hormones. It does not diagnose a mental health condition.
Why has my libido changed?
Low testosterone and low estradiol are both commonly associated with reduced libido in women, and stress can play a role too. Because this panel measures all of them, it can help pinpoint which may be contributing.
Could an imbalance between estrogen and progesterone contribute to my symptoms?
Possibly. When estradiol is high relative to progesterone, people commonly report tender breasts, water retention, irritability and difficult cycles. This panel measures both hormones and their relationship, which is the way to understand whether that pattern fits you.
Can stress affect my estrogen or progesterone?
Stress hormones and sex hormones do not operate in separate silos. They interact. That is why cortisol is included alongside estradiol and progesterone here, so you can see them in context rather than in isolation.
Why saliva instead of blood?
Saliva measures the free, bioavailable fraction of these hormones, the portion that reaches your tissues, which ZRT describes as relating more closely to symptoms. It is also collected easily at home.
Do I need to collect on a specific day of my cycle?
If you still have menstrual cycles, the timing of collection matters for an accurate read of progesterone. Your kit instructions explain when to collect, and the Flourish team can help if you are unsure.
Can I use this if I am on hormone therapy?
It depends on the delivery method. Saliva works well for monitoring topical creams or gels. It is not appropriate for sublingual or troche hormones, which can falsely raise saliva levels, and ZRT recommends blood spot testing instead. Ask the Flourish team if you are unsure which fits.
Should I test my hormones before starting BHRT?
A baseline before starting, and re-testing to monitor afterward, is a common approach. ZRT designs these panels both to assess baseline levels before hormone therapy and to monitor dosing. Whether and how to start any therapy is a decision for you and your provider.
Does this test include thyroid?
No. This saliva panel covers sex and adrenal hormones only. If you want thyroid markers too, a combined saliva and blood spot profile is the better fit.
How long until I get results?
Typically about two weeks after the lab receives your samples.
Do I need a doctor's order to buy it?
No appointment is required to purchase the kit or receive your results. A Flourish pharmacist or nutritionist review is available if you would like guidance.
Will this diagnose a medical condition?
No. It is a wellness and monitoring tool that gives you and your provider objective information. It is not a stand-alone diagnostic test.
If you are unsure whether this panel fits your symptoms or goals, or whether saliva or blood spot is right for you, contact the Flourish team before ordering. We will help you determine whether this test, or another option, makes the most sense for your situation. You can also explore our Women's Hormones resources and the Hormone Vitality Program.
Our goal is to help you choose the right test, not simply sell you one.
Based on testing performed by ZRT Laboratory.
The Food and Drug Administration has not evaluated these statements. Flourish-supported products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using this product.